Key words: Cassia auriculata, Periodontal pathogens, Antibacterial activity INTRODUCTION: Periodontitis is a chronic inflammatory disease of the supporting tissues of the teeth which is caused by complex interaction between various micro-organisms and host immune response [1]. Cassia auriculata against anaerobic periodontal pathogens. Safety pharmacology studies help in identifying preclinical adverse drug reactions. In the present study, the antioxidant activity of C. auriculata aqueous leaf extract (CLEt) was evaluated in streptozotocin-induced mild diabetic (MD) and severe diabetic (SD) rats. Keywords: Cassia auriculata, Phytochemical compounds, Pharmacological activity and PASS prediction. The flower of the shrub is preliminary way the genetic diversity of Cassia auriculata seeds collected from fourteen different locations of India. Cassia auriculata is a natural herb belongs to family Fabaceae and locally called as ‘avaram’. In tune with this effort, the objective set for the present investigation is to estimate the phenolic and flavonoid contents in flower extracts of Cassia auriculata and Cassia siamea. Thus, prepared extracts were subjected to phytochemical investigation and evaluated for antioxidant effect using DPPH and antisolar efficacy. The plant has been reported to antibacterial, hypoglycemic and microbicidal activity The Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism 2017, Biomedicine and Pharmacotherapy Download PDF View details Its seeds can be used in similar manner as flowers. Table - III: Protection Performance of Cassia Auriculata Flower extract on mild steel in 1MHCl for 3 hrs at different temperatures S. No. The qualitative phytochemical analysis of the extract showed the presence of flavonoids, alkaloids, tannins, glycosides, terpenoids, phenols, carbohydrates, and proteins. The phytochemical screening and antioxidant activity were made in these extracts. The ethanol and methanol extracts of Cassia auriculata flowers were screened for antioxidant activity. Cassia auriculata, commonly known as “Tanner’s cassia,” is widely used in Indian folk medicine for the treatment of diabetes mellitus. It is one of the main constituents of ‘Kalpa herbal tea ’and has proven antidiabetic action [3]. The shrub is specially famous for its attractive yellow flowers which are used in the treatment of skin disorders and body odour. We carried out routine safety pharmacology with focus on cardiovascular variables and pharmacokinetic herb-drug interaction studies on rats fed with standardized traditional hydro-alcoholic extract and technology-based supercritical extract of Cassia auriculata for 12 weeks. Introduction Cassia auriculata is one of the herbaceous plants that found throughout central and southern India, also cultivated in Punjab, Haryana, Uttar Pradesh and … By the help of Cassia auriculata leaves extract with silver nitrate source materials, silver NPs were prepared by using Reflux method. Cassia auriculata is frequently used for the treatment of infections, pathologies of the skin disease, fever, liver injury and others diseases involving inflammation and pain. roots, leaves, flowers, bark and unripe fruits). The ethanol leaf extract of the plants at concentration 80 mg/ml can be compared to the commercial antibiotic, penicillin against Bacillus subtilis. Cassia auriculata ESBL are plasmid mediated enzymes which are capable of commonly known as tanners Cassia, also known as hydrolyzing and inactivating a wide variety of-lactams “Avaram” in Tamil is a shrub that belongs to the including third generation cephalosporins (3GC),Caesalpiniaceae family [13]. Cassia now generally includes the largest species of … Cassia auriculata leaves were collected from Srirangapatnam, Mysuru, Karnataka, India, (Geographical Coordinates: 12.4237 N, 76.6829 E) in October 2019. The fresh and young leaf samples of Cassia auriculata was collected, washed thoroughly with sterile double distilled water (DDW) and surface sterilized with 0.1 % HgCl2 for 2 - 3 min under the hood of laminar air flow. Cassia is an indigenous medicinal plant genus, in which Cassia auriculata have large biodiversity in south India and Cassia fistula in north India. Mol Cell Biochem 2003;243:23-8. The plant is mainly valued for its cathartic properties and is specially useful in habitual constipation. Asia Pacific J Clin Nutr (2002) 11(2): 157–163 Original Article Effect of Cassia auriculata leaf extract on lipids in rats with alcoholic liver injury Rajagopal Senthil Kumar 1MSc, Manickam Ponmozhi MSc, Periyasamy Viswanathan2MD and Namasivayam Nalini1MSc, PhD 1Department of Biochemistry, Annamalai University, Annamalainagar, Tamilnadu, India 2Department of Pathology, Rajah Muthiah … View abstract. In the present study the antidiabetic potential of aqueous and ethanol extract of Cassia auriculata L. flowers was assessed in alloxan-induced diabetic rats. The powder of the herb, mixed with honey is equally efficacious in such a case. Cassia auriculata Linn., belonging to the family Caesalpiniaceae, is commonly known as Tanner’s cassia. Latha M, Pari L. Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin. The antioxidant activity was determined by an improved assay based on the decolorization of the radical monocation of 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. The preliminary qualitative screening revealed the presence of important secondary metabolites in both the species responsible for the antioxidant potential. Oral administration of 0.45 g/kg body weight of the aqueous extract of the flower for 30 days resulted in a significant reduction in blood glucose and an increase in plasma insulin, but in the case of 0.15 and 0.30 g/kg, was not significant. Cassia auriculata commonly known as Tanner’s assia and ‘Aavaarai in tamil’ is a weed widely distributed in dry regions of Madhya Pradesh, Tamil Nadu and Rajasthan. Senna auriculata is a leguminous tree in the subfamily Caesalpinioideae.It is commonly known by its local names matura tea tree, avaram or ranawara, (Kannada: ಆವರಿಕೆ āvarike, Telugu: తంగేడు taṃgēḍu, Tamil: ஆவாரை āvārai) or the English version avaram senna.It is the State flower of Telangana. 7172-.7274 e-ISSN:2581-6063 (online), ISSN:0972-5210 ANTICANCER ACTIVITY OF TAMARINDUS INDICA FRUIT PULP AND CASSIA AURICULATA LEAVES EXTRACT AGAINST BREAST CANCER CELL LINE P. Durga1, R. Malarkodi2, D. Sudha3, C. Shamaila Afreen4 and Anooj E.S.5* 1,2,4PG and Research Department of Biochemistry, Marudhar Kesari Jain … The seeds of Cassia auriculata find their application in purulent ophthalmic that is inflammation of the eye or conjunctiva. Only Cassia alata and Cassia auriculata has exhibited antifungal activity. Cassia auriculata Linn. Cassia auriculata L. commonly known as tanner's cassia, also known as “avaram” in Tamil language is a shrub belongs to the Caesalpiniaceae family. Urinary discharge, Cassia auriculata is used in Ayurvedic medicine as “Avarai Panchaga choornam” (mixture of five parts of the shrub i.e. The Cassia Effect of aqueous and ethanol extracts of Cassia auriculata L. flowers 102 0 20 40 60 80 100 120 A q u eo u s ic ex tr t E th ano l e xt r a c t Antioxidant activity (%) Figure 1: Antioxidant activity of aqueous and ethanol extract of C. auriculata flowers Data were presented as mean ± SD of each three replicates Cassia auriculata is effective remedy for diabetes. SUMMARY. 2, 2020 pp. the antibacterial properties of flowers of Cassia auriculata. These leaves are mainly used to treat anthelmentic infections, ulcer, leprosy and other skin diseases. It is shrub, having smooth bark and mostly seen in the India, Sri Lanka and other Asian countries. It is a small bush, which grows wild in South India with flowers and pods throughout the year (Matthew, 1983). Abstract: Objectives: The present study deals with an in-vitro screening for the anti-solar potential of aqueous and ethanolic extracts of Cassia auriculata using the UV method.Methods: Aqueous and ethanolic extracts were prepared. Cassia auriculata flowers Having known the pharmacological significance Cassia auriculata, an earnest attempt has been made to Cassia auriculata L. (Caesalpiniaceae) is widely used from the ancient period to treat diabetes mellitus. The aerial parts of CA were subjected to solvent extraction, and the extracts were fractionised by gas chromatography and mass spectrometry analysis for its phytochemical content. Plant Archives Volume 20 No. Cassia Auriculata Flowers . Cassia fistula has no effect against all tested fungi. A short-term toxicity assessment was also conducted in healthy rats to examine toxic effects of the extract. Thin-layer chromatography The TLC studies of the ethanol extract of Cassia auriculata showed the presence of well-separated Cassia angustifolia (senna), a native plant of Yemen, Somalia and Arabia and now cultivated in other parts of the world, has a variety of medicinal uses in Unani as well as other traditional systems of medicine. In the present study, the antioxidant activity of C. auriculata aqueous leaf extract (CLEt) was evaluated in streptozotocin-induced mild diabetic (MD) and severe diabetic (SD) rats. Twenty gram of sterilized leaf samples were taken and cut into small pieces. Cassia auriculata L. (Caesalpiniaceae) is widely used from the ancient period to treat diabetes mellitus. Cassia auriculata belonging to Caesalpiniaceae (Fabaceae) is common plant in India, widely used in Ayurveda medicine as a tonic and remedy for diabetes. The present communication constitutes a review on the medicinal properties and pharmacological actions of Cassia auriculata and Cassia fistula used in … It is widely used in The present study was designed to evaluate the antimicrobial, radical scavenging and chemical composition of aerial parts of Cassia auriculata.Three hundred grams of powdered material of C. auriculata extracted with methanol (CAMEt), C-18 silica gel based column chromatography was used to purify CAMEt using n-hexane, ethyl acetate and methanol fractions. commonly known as ‘Tanner’s Cassia’ (Ceasalpinaceae) or Avartaki in Ayurveda is an annual or biennial shrub found throughout India in open forests. The leaves were thoroughly washed and dried at room temperature for about 15 days before being ground into a fine powder. It belongs to the family Caesalpiniaceae. Cassia is a genus of flowering plants in the legume family, Fabaceae, and the subfamily Caesalpinioideae.Species are known commonly as cassias.Cassia is also the English common name of some species in the genus Cinnamomum of the family Lauraceae.Species of the genera Senna and Chamaecrista were previously included in Cassia. Cassia auriculata , Linn (Caesalpiniaceae) commonly known as Tanners Cassia [Avaram] is a shrub with large bright yellow flowers, growing wild in Central Provinces and Western peninsula parts of India [2] . Pari L, Latha M. Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats. '\and enrofloxacin (5 mg/ml). Singapore Med J 2002;43:617-21. V. Kavimani et al J. Chem. The present study is an attempt to evaluate the in vitro anti-inflammatory and in silico anticancer potentials of the plant Cassia auriculata (CA). The plant was unambiguously identified by Dr. Murali Mahadevamurthy. 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